A Clinical Trial of MK-4082 in Healthy Participants (MK-4082-005)
Summary
Researchers are looking for new weight loss medicines for people with higher body weight. The trial medicine, MK-4082, is different from similar weight loss medicines because people take it as a pill instead of an injection. Before giving a trial medicine to participants with a health condition, researchers first do trials in healthy participants to find a safe dose level (amount) of the trial medicine. The goal of this study is to learn what happens to MK-4082 in a person's body over time. Researchers will compare what happens to levels of MK-4082 in people's blood when it is taken without (Period 1) and with (Period 2) another medicine called diltiazem. Researchers also want to learn about the safety of MK-4082 taken with and without diltiazem and if people tolerate them.
Timeline
- Start
- 2026-07-13
- Primary completion
- 2026-09-28
- Completion
- 2026-09-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Diltiazem | Small molecule | — | Oral |
| Subject | MK-4082 | Unknown | — | Oral |
| Background | Ondansetron | Other / unclassified | — | — |
Indications
No indication recorded.