drugset / Trial / NCT07703098
Hydrocortisone Versus Methylprednisolone for the Treatment of Glucocorticoid-Induced Adrenal Insufficiency
Phase 4
Not yet recruiting
66 enrolled
University Medical Centre Ljubljana
University of Ljubljana · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This study aims to compare the use of methylprednisolone and hydrocortisone as replacement therapies in patients with glucocorticoid-induced adrenal insufficiency. The primary goal is to evaluate and compare the recovery of the hypothalamic-pituitary-adrenal (HPA) axis.
Timeline
- Start
- 2026-09-01
- Primary completion
- 2029-09-01
- Completion
- 2030-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Hydrocortisone | Other / unclassified | 15 mg | — |
| Subject | Methylprednisolone | Other / unclassified | 3 mg | — |