drugset / Trial / NCT07707258
Remimazolam Combined With Oliceridine for Sedation in Elderly Patients Undergoing Gastrointestinal Endoscopy
Not yet recruiting
240 enrolled
Baoshan Branch, Renji Hospital, Shanghai Jiao Tong University School of Medicine
RandomizedParallel-groupDouble-blindTreatment
Summary
This study aims to evaluate the sedative efficacy and safety of remimazolam combined with oliceridine in elderly patients undergoing painless gastrointestinal endoscopy. Elderly patients often face higher risks of respiratory and hemodynamic depression during clinical sedation. This trial will investigate whether the combination of remimazolam and oliceridine can provide stable sedation, maintain stable vital signs, and reduce the incidence of adverse events such as hypoxemia and postoperative cognitive fluctuation in this vulnerable population.
Timeline
- Start
- 2026-07-05
- Primary completion
- 2026-09-01
- Completion
- 2026-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Oliceridine | Other / unclassified | — | Intravenous |
| Background | Remimazolam | Small molecule | — | Intravenous |
Indications
No indication recorded.