drugset / Trial / NCT07707258

Remimazolam Combined With Oliceridine for Sedation in Elderly Patients Undergoing Gastrointestinal Endoscopy

NCT07707258

RandomizedParallel-groupDouble-blindTreatment

Summary

This study aims to evaluate the sedative efficacy and safety of remimazolam combined with oliceridine in elderly patients undergoing painless gastrointestinal endoscopy. Elderly patients often face higher risks of respiratory and hemodynamic depression during clinical sedation. This trial will investigate whether the combination of remimazolam and oliceridine can provide stable sedation, maintain stable vital signs, and reduce the incidence of adverse events such as hypoxemia and postoperative cognitive fluctuation in this vulnerable population.

Timeline

Start
2026-07-05
Primary completion
2026-09-01
Completion
2026-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Oliceridine Other / unclassified Intravenous
Background Remimazolam Small molecule Intravenous

Indications

No indication recorded.