drugset / Trial / NCT07712783
Lateral QL Block vs Intrathecal Morphine for Cesarean Section
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Effective postoperative analgesia after cesarean delivery is essential for maternal recovery, early mobilization, breastfeeding, and maternal-infant bonding. Although intrathecal morphine (ITM) is considered the gold standard for post-cesarean analgesia, its use is associated with opioid-related adverse effects. Ultrasound-guided lateral quadratus lumborum block (QLB-I) has emerged as a promising alternative. This randomized, double-blind, non-inferiority trial aims to compare the postoperative analgesic efficacy of lateral QLB-I with ITM. Secondary outcomes include postoperative opioid consumption, pain scores, opioid-related adverse effects, quality of recovery (ObsQoR-11T), and maternal satisfaction.
Timeline
- Start
- 2026-07-15
- Primary completion
- 2026-09-01
- Completion
- 2026-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Morphine | Other / unclassified | 0.01 mg/kg | Intravenous |
| Background | Morphine | Other / unclassified | 0.015 mg/kg | Intravenous |
Indications
No indication recorded.