drugset / Trial / NCT07713134
Comparison of the Efficacy and Safety of Oliceridine and Sufentanil in Patients Undergoing Outpatient Hysteroscopy
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study aimed to investigate the safety and efficacy of oliceridine compared with sufentanil in outpatient hysteroscopy.
Timeline
- Start
- 2025-08-01
- Primary completion
- 2026-05-20
- Completion
- 2026-06-30
Publications
- Background Chen L, Xie K, Ji K, Long M, Zhang Y, He K. Effects of Oliceridine Versus Sufentanil on Hemodynamic Stability in Elderly Hypertensive Patients During Laryngeal Mask Airway Anesthesia: A Randomized Controlled Trial. Drug Des Devel Ther. 2025 Oct 22;19:9515-9522. doi: 10.2147/DDDT.S547901. eCollection 2025.
- Background Tan HS, Habib AS. Oliceridine: A Novel Drug for the Management of Moderate to Severe Acute Pain - A Review of Current Evidence. J Pain Res. 2021 Apr 14;14:969-979. doi: 10.2147/JPR.S278279. eCollection 2021.
- Background Yi K, Sun W, Yu W, Chen S. Overview and Prospects of the Clinical Application of Oliceridine. Drug Des Devel Ther. 2025 Jun 26;19:5415-5430. doi: 10.2147/DDDT.S525471. eCollection 2025.
- Background Lei X, Zhang T, Huang X. Comparison of a single intravenous infusion of alfentanil or sufentanil combined with target-controlled infusion of propofol for daytime hysteroscopy: a randomized clinical trial. Ther Adv Drug Saf. 2024 Oct 31;15:20420986241292231. doi: 10.1177/20420986241292231. eCollection 2024.
- Background Anggraeni TD, Widyatama A, Soetikno V, Davis GS, Setiaka HA, Sekarlangit MC. Efficacy of Oral Paracetamol Compared with Oral Ketoprofen for Pain Management in Office Hysteroscopy: A Double-Blind, Randomized Clinical Trial. Medicina (Kaunas). 2026 Jan 14;62(1):170. doi: 10.3390/medicina62010170.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Oliceridine | Other / unclassified | 0.04 mg/kg | — |
| Comparator | Sufentanil | Other / unclassified | 0.15 ug/kg | — |
Indications
No indication recorded.