drugset / Trial / NCT07745361

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

NCT07745361 ↗

Phase 2 Recruiting 25 enrolled Monte Rosa Therapeutics, Inc
NaSingle-groupOpen-labelTreatment

Summary

This Phase 2, open-label, multicenter study is conducted in patients with castration-resistant prostate cancer. Patients in this study receive MRT-2359, an investigational oral medicine, in combination with apalutamide, an oral medicine used to treat prostate cancer. The main purpose of the study is to assess whether this treatment combination can lower prostate-specific antigen (PSA) The study will also evaluate the safety and tolerability of the treatment combination and assess additional measures of anti-tumor activity.

Timeline

Start
2026-08-18
Primary completion
2027-10
Completion
2028-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Apalutamide Small molecule — Oral
Subject MRT-2359 Other / unclassified — Oral