drugset / Trial / NCT07790913

Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and Lymphoma

NCT07790913 ↗

Phase 2 Not yet recruiting 100 enrolled St. Jude Children's Research Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is evaluating whether a weight-loss medication (PHEN/TOP) combined with healthy lifestyle counseling is safe, well tolerated, and can help reduce obesity in adolescents and young adults who are in remission from ALL, Hodgkin lymphoma, or non-Hodgkin lymphoma. Participants are randomly assigned to receive either PHEN/TOP plus counseling or counseling alone for 24 weeks and are followed for up to 52 weeks.

Timeline

Start
2026-10
Primary completion
2030-08
Completion
2031-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Phentermine Small molecule — Oral
Subject Topiramate Small molecule — Oral