drugset / Trial / NCT07790913
Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and Lymphoma
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is evaluating whether a weight-loss medication (PHEN/TOP) combined with healthy lifestyle counseling is safe, well tolerated, and can help reduce obesity in adolescents and young adults who are in remission from ALL, Hodgkin lymphoma, or non-Hodgkin lymphoma. Participants are randomly assigned to receive either PHEN/TOP plus counseling or counseling alone for 24 weeks and are followed for up to 52 weeks.
Timeline
- Start
- 2026-10
- Primary completion
- 2030-08
- Completion
- 2031-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Phentermine | Small molecule | — | Oral |
| Subject | Topiramate | Small molecule | — | Oral |