Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes

Summary

Type 1 diabetes (T1D) in children involves autoimmune destruction of pancreatic ß- cells, leading to insulin deficiency. Verapamil is an L-type calcium channel blocker that has been used for decades to treat hypertension and certain cardiac conditions. Recent research has revealed its potential as a ß- cell-protective agent. Hence this study will evaluate the effect of once-daily oral verapamil on pancreatic ß- cell reserve , glycemic metrics and daily insulin requirements in children and adolescents with T1D.

Timeline

Start

2026-08-20

Primary completion

2027-02-20

Completion

2027-03-20

Drugs

Indications