drugset / Trial / NCT07822256

Chlorhexidine vs Essential Oil Mouthwash for Plaque Control

NCT07822256 ↗

Completed 60 enrolled Rehman Medical Institute - RMI
RandomizedParallel-groupSingle-blindTreatment

Summary

Dental plaque is a sticky film of bacteria that forms on teeth and can lead to gum disease if it is not removed regularly. Brushing and flossing help control plaque, but many people also use a mouthwash to help clean areas that are hard to reach. This study compares two common types of mouthwash to see which one works better at reducing plaque: a mouthwash containing chlorhexidine (a medicated antibacterial ingredient) and a mouthwash containing essential oils (natural plant-based ingredients). Both are widely used, but they work in different ways and may cause different side effects. Sixty patients between the ages of 15 and 25 who had gum inflammation (gingivitis) took part. Half of the patients used the chlorhexidine mouthwash twice a day, and the other half used the essential oil mouthwash twice a day, for three months. Researchers measured the amount of plaque on each patient's teeth at the start of the study and again after three months, using a standard scoring method. They also recorded how well patients stuck to the mouthwash routine and any side effects they experienced, such as changes in taste, staining of the teeth, or a burning feeling in the mouth. The goal of this study is to help patients and dental care providers understand the benefits and drawbacks of each mouthwash, so they can choose the option that best fits their needs - whether that is stronger plaque control for a short period of time, or a milder option that may be more comfortable for longer-term use.

Timeline

Start
2026-02-03
Primary completion
2026-08-10
Completion
2026-08-28

Drugs

EvaluationDrugModalityDoseRoute
Comparator Chlorhexidine gluconate Other / unclassified 0.2 % Oral
Subject Essential Oil mouthwash Unknown — Oral

Indications