drugset / Trial / NCT07825064
Cevostamab in Combination With Pomalidomide and Dexamethasone After BCMA- Targeting CAR T-Cell Therapy in Participants With Previously Treated Multiple Myeloma
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to assess the efficacy and safety of cevostamab in combination with pomalidomide and dexamethasone (CevosPd) in patients with multiple myeloma (MM) who have received one to four prior lines of therapy and have been exposed to an anti-cluster of differentiation 38 (CD38) antibody, lenalidomide, a proteasome inhibitor (PI) and a B cell maturation antigen (BCMA)-targeting chimeric antigen receptor (CAR) T-cell therapy.
Timeline
- Start
- 2026-10-01
- Primary completion
- 2029-04-13
- Completion
- 2031-01-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cevostamab | Monoclonal antibody | — | — |
| Subject | Pomalidomide | Other / unclassified | — | — |
| Background | Dexamethasone | Small molecule | — | — |
| Background | Tocilizumab | Monoclonal antibody | — | — |