drugset / Trial / NCT07840365

Optimal Anti-Thrombotic Management Following Percutaneous Left Atrial Appendage Occlusion

NCT07840365 ↗

Phase 3 Recruiting 234 enrolled Texas Cardiac Arrhythmia Research Foundation
RandomizedParallel-groupOpen-labelPrevention

Summary

This randomized study was designed to compare two antithrombotic regimens (long-term half-dose apixaban vs long-term aspirin after 45-days of full-dose apixaban) after successful Watchman implantation.

Timeline

Start
2026-09-01
Primary completion
2028-12-15
Completion
2029-09-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Apixaban Small molecule 2.5 mg —
Comparator Apixaban Small molecule 5 mg —
Comparator Aspirin Small molecule — —

Indications