drugset / Trial / NCT07843550
A Phase 1/2 Trial Of Larotrectinib And Pembrolizumab In Patients With Solid Tumors Previously Treated With Immune Checkpoint Inhibitor Monotherapy
NaSingle-groupOpen-labelTreatment
Summary
This is a single-center, open-label Phase 1/2 trial evaluating the safety and efficacy of the combination of larotrectinib and pembrolizumab in patients with advanced/metastatic lung adenocarcinoma or melanoma.
Timeline
- Start
- 2027-03-01
- Primary completion
- 2027-07-13
- Completion
- 2029-07-13
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Larotrectinib | Small molecule | — | — |
| Subject | Pembrolizumab | Monoclonal antibody | — | Intravenous |