(Z)-Endoxifen in Girls With MAS-Associated Peripheral Precocious Puberty

Summary

The goal of this clinical trial is to evaluate the safety, tolerability, and blood levels of (Z)-endoxifen in girls with McCune-Albright Syndrome that have peripheral precocious puberty. The main question it aims to answer \[is/are\]: Are there any safety concerns? Is there any evidence of efficacy? There is no comparison group. Participants will: * take a capsule once a day for 3 months; * have doctor visits (tele-health and in-person); * blood samples collected; and * complete questionnaires

Timeline

Start

2027-03

Primary completion

2028-06

Completion

2028-09

Drugs

Indications