Lersivirine
Trials 9 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 15 trials | ||||||
| Phase 1 | NCT01603485 | Jun → Aug 2012 | — | Pfizer | Completed | No outcome recorded |
| Phase 1 | NCT01220232 | Nov 2010 → Jan 2011 | — | Pfizer | Completed | No outcome recorded |
| Phase 1 | NCT01099748 | May → Jun 2010 | — | Pfizer | Completed | No outcome recorded |
| Phase 1 | NCT00925535 | May → Aug 2010 | — | Pfizer | Completed | No outcome recorded |
| Phase 1 | NCT00936871 | Jan → Mar 2010 | — | Pfizer | Completed | No outcome recorded |
| Phase 24 trials | ||||||
| Phase 2 | NCT01254656 | Feb 2011 → Apr 2013 | — | Pfizer | Terminated | No outcome recorded |
| Phase 2 | NCT00823979 | Mar 2009 → Oct 2012 | — | Pfizer | Terminated | No outcome recorded |
| Phase 2 | NCT00824421 | Feb 2009 → Oct 2011 | — | Pfizer | Completed | No outcome recorded |
| Phase 2 | NCT00348673 | Feb 2006 → Feb 2007 | — | Pfizer | Completed | No outcome recorded |
Also used as a comparator or background therapy in 3 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT01230385 Comparator | Oct 2010 → May 2011 | — | Pfizer | Completed | No outcome recorded |
| Phase 1 | NCT01050751 Comparator | Feb → Mar 2010 | — | Pfizer | Completed | No outcome recorded |
| Phase 1 | NCT00784420 Comparator | Sep → Nov 2008 | — | Pfizer | Completed | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 13 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Lersivirine | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01099748 ↗ |
| Known as | Lersivirina | ChEMBL registry synonym — accepted as the source's own label CHEMBL571987 ↗ |
| Known as | UK 453,061 | “Open-Label, Randomized, 2-Way Crossover Study To Estimate The Pharmacokinetics And Bioavailability Of Lersivirine (UK 453,061) Administered As A Single 750 Mg Tablet And 3 X...” NCT01050751 ↗8“A Phase 1, Randomized, Single Dose, Placebo And Active Controlled, 3-Way Crossover Study To Evaluate The Effect Of A Single Oral Dose Of Lersivirine (UK-453,061) On Qt...” NCT00936871 ↗ “Open-Label, Randomized, Crossover Study to Estimate the Pharmacokinetics, Bioavailability and Effect of Food on Single Dose Modified-release Lersivirine (UK-453,061) 500 mg in...” NCT01603485 ↗ “Open Label, Single-Sequence Study To Estimate The Effect Of Lersivirine (UK-453,061) On S- And R-Methadone In Subjects Receiving Chronic Methadone Treatment” NCT01099748 ↗ “UK-453,061 500 mg tablets PO QD + Tenofovir DF 300 mg/Emtricitabine 200 mg tablets PO QD.” NCT00824421 ↗ “Drug Interaction Study Between Rifabutin And Lersivirine (UK-453,061)” NCT00925535 ↗ |
| Modality | Small molecule | — CHEMBL571987 ↗ |
| Route | Oral | “UK-453,061 500 mg tablets PO QD” NCT00824421 ↗ |