drugset / Trial / NCT01099748
Estimate The Effect Of Lersivirine On The Pharmacokinetics Of S- And R-Methadone
Non-randomizedCrossoverOpen-labelTreatment
Summary
The objective of this study is to estimate the effect of lersivirine on the pharmacokinetics of R-methadone and S-methadone and to investigate the safety and tolerability of lersivirine when co-administered with methadone. Symptoms of methadone withdrawal will also be assessed.
Timeline
- Start
- 2010-05
- Primary completion
- 2010-06
- Completion
- 2010-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lersivirine | Small molecule | 1000 mg | — |
| Comparator | Methadone | Other / unclassified | 50 mg | — |
| Comparator | Methadone | Other / unclassified | 150 mg | — |
Indications
No indication recorded.