Drugs / BMS-986142
last change May 2023 re-read 2 minutes ago

BMS-986142

Small molecule targets BTK via inhibition

Developed for
rheumatoid arthritis · Sjogren syndrome
Investigated by
Bristol-Myers Squibb

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT02880670 Aug → Sep 2016 arthritic joint disease Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT02832180 May → Oct 2016 arthritic joint disease Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT02762123 May → Aug 2016 rheumatoid arthritis Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT02456844 May → Jul 2015 rheumatoid arthritis Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT02257151 Sep 2014 → Aug 2015 Bristol-Myers Squibb Completed No outcome recorded
Phase 22 trials
Phase 2 NCT02843659 Oct 2016 → Jul 2017 Sjogren syndrome Bristol-Myers Squibb Terminated No outcome recorded
Phase 2 NCT02638948 Feb 2016 → May 2018 rheumatoid arthritis Bristol-Myers Squibb Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as BMS-986142 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02762123
6

NCT02843659

NCT02257151

NCT02832180

NCT02456844

NCT02638948

NCT02880670

Action Inhibit “This study examined safety, efficacy, and pharmacokinetics of BMS-986142, an oral, reversible BTK inhibitor.” PMID 38251590 May 2023
1

“Tyrosine-protein kinase BTK inhibitor” CHEMBL3900554

Modality Small molecule CHEMBL3900554
Route Oral “BMS-986142 or placebo Single dose oral Solution or spray dried dispersion as specified” NCT02257151
Target BTK “Tyrosine-protein kinase BTK inhibitor” CHEMBL3900554