Drugs / POLIGLUSAM
POLIGLUSAM
Trials 16
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT06457360 | Nov 2023 → Jan 2024 | cirrhosis of liver | British University In Egypt | Completed | No outcome recorded |
| Phase 12 trials · 1 missed | ||||||
| Phase 1 | NCT06525363 | Aug 2024 → Feb 2025 | periodontal disorder | Deraya University | Completed | No outcome recorded |
| Phase 1 | NCT06072716 | Jan → Jul 2023 | oral candidiasis | Yasmine gamil | Completed | Missed primary |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT03712371 | Jan 2019 → Jul 2020 | prostate cancer | Medical University of South Carolina | Terminated | No outcome recorded Stop: Enrollment |
| Phase 21 trial | ||||||
| Phase 2 | NCT07702474 | Apr → Nov 2009 | aphthous stomatitis, ulcerative stomatitis | Kerman University of Medical Sciences | Completed | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT04319575 | Dec 2018 → Apr 2020 | suppurative periapical periodontitis | Dr. D. Y. Patil Dental College & Hospital | Unknown | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT07499115 | Apr → Jul 2026 overdue | gingivitis | Colgate Palmolive | Not yet recruiting | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT05661708 | Dec 2022 → Mar 2024 | — | Erzincan Military Hospital | Completed | No outcome recorded |
| Phase not applicable8 trials | ||||||
| — | NCT07544004 | Jul 2026 → Jan 2027 expected | — | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT06714695 | Nov 2024 → Mar 2025 overdue | — | Al-Azhar University | Recruiting | No outcome recorded |
| — | NCT06491992 | Jul → Sep 2024 overdue | — | October 6 University | Recruiting | No outcome recorded |
| — | NCT06567301 | Oct 2023 → May 2025 overdue | osteoarthritis, knee | Cairo University | Recruiting | No outcome recorded |
| — | NCT03724266 | Oct 2018 → May 2020 | — | Cairo University | Unknown | No outcome recorded |
| — | NCT03588351 | Jan → Aug 2018 | dental pulp necrosis | Ain Shams University | Unknown | No outcome recorded |
| — | NCT02890277 | Jan 2016 → Dec 2017 | vulvar intraepithelial neoplasia | Jinan Military General Hospital | Unknown | No outcome recorded |
| — | NCT02413125 | Feb → Jun 2015 | sinusitis | University of Virginia | Unknown | No outcome recorded |
| Comparator or background therapy4 trials | ||||||
| Phase 3 | NCT02789033 Comparator | Jun → Aug 2015 | ulcer of lower limbs | University of Guadalajara | Completed | No outcome recorded |
| Phase 3 | NCT02591017 Background | Feb 2015 → Jul 2017 | — | University Hospital, Basel, Switzerland | Terminated | No outcome recorded Stop: Enrollment |
| — | NCT06755528 Background | Dec 2024 → Feb 2025 overdue | fallopian tube disorder | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT06758440 Comparator | Mar 2023 → Mar 2024 | — | Minia University | Completed | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 21 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | POLIGLUSAM | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108133 ↗ |
| Known as | Chitosan | “Recently, a novel commercially available irrigation solution, the ChitoRhino, has been developed with chitosan, a natural polysaccharide demonstrated to have antibacterial and...” NCT02413125 ↗19“using Chitosan mixed with calcium hydroxide or Triple Antibiotic Paste at 3,6 and 12 months.” NCT04319575 ↗ |
| Known as | FEMA NO. 4946 | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108133 ↗ |
| Action | Inhibit | “Chitosan was found to suppress pro-inflammatory cytokines and decreased peripheral nerve edema” NCT06491992 ↗ |
| Modality | Other / unclassified | “high-molecular-weight linear polycationic heteropolysaccharide” NCT02789033 ↗ |
| Route | Intranasal | “ketamine/chitosan spray nasal” NCT02591017 ↗ |