Efficacy of 5% Chitosan Nanoparticle Paste in the Treatment of Recurrent Aphthous Stomatitis

Phase 2 Completed 30 enrolled Kerman University of Medical Sciences

RandomizedParallel-groupSingle-blindTreatment

Summary

The purpose of this study is to evaluate the therapeutic clinical efficacy of a synthesized 5 wt.% chitosan nanoparticle paste compared to a standard topical corticosteroid (triamcinolone acetonide 0.1% oral paste) in patients suffering from minor recurrent aphthous stomatitis. The study specifically monitors changes in clinical ulcer diameter and pain reduction.

Timeline

Start: 2009-04-21
Primary completion: 2009-11-03
Completion: 2009-12-01

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	POLIGLUSAM	Other / unclassified	5 %	Topical
Comparator	Triamcinolone Acetonide	Other / unclassified	0.1 %	Topical

Efficacy of 5% Chitosan Nanoparticle Paste in the Treatment of Recurrent Aphthous Stomatitis

Summary

Timeline

Drugs

Indications