Drugs / Mizoribine
Trials 5 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial | ||||||
| Phase 2 | NCT02005757 | Nov 2013 → Jun 2016 | rheumatoid arthritis | Chong Kun Dang Pharmaceutical | Unknown | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT02256150 | Nov 2014 → Mar 2019 | lupus nephritis | Asahi Kasei Therapeutics Corporation | Completed | No outcome recorded |
| Phase 3 | NCT02257697 | Nov 2014 → Nov 2018 | nephrotic syndrome | Asahi Kasei Therapeutics Corporation | Completed | No outcome recorded |
| Phase 42 trials | ||||||
| Phase 4 | NCT06114953 | Jan 2023 → Jan 2025 | disease related to solid organ transplantation | Lee's Pharmaceutical Limited | Unknown | No outcome recorded |
| Phase 4 | NCT05293704 | May 2022 → Dec 2023 | disease related to solid organ transplantation, polyomavirus infectious disease | Lee's Pharmaceutical Limited | Unknown | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 3 | NCT02373202 Background | Feb 2015 → Nov 2016 | rheumatoid arthritis | Sanofi | Completed | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 9 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Mizoribine | “The purpose of this study is to access the efficacy and safety of Mizoribine 150mg qid and 50mg tid in active rheumatoid arthritis patients unsuccessfully treated with...” NCT02005757 ↗ |
| Known as | Bredinin | ChEMBL registry synonym — accepted as the source's own label CHEMBL245019 ↗ |
| Known as | Mizoribina | ChEMBL registry synonym — accepted as the source's own label CHEMBL245019 ↗ |
| Known as | MZR | “BACKGROUND: Mizoribine (MZR) was effective and safe for living Chinese donor kidney transplantation (LDKT) on tacrolimus-based treatment 1 year after transplantation.” PMID 31155174 ↗ Jun 20192“Mizoribine (MZR) is a novel agent used in long-term immunosuppressive therapy” PMID 36990111 ↗ Jun 2023 “Drug: Mizoribine (MZR)” NCT02256150 ↗ |
| Known as | NSC-289637 | ChEMBL registry synonym — accepted as the source's own label CHEMBL245019 ↗ |
| Action | Inhibit | “GMP synthase [glutamine-hydrolyzing] inhibitor” CHEMBL245019 ↗ |
| Modality | Small molecule | — CHEMBL245019 ↗ |
| Route | Oral | “Oral administration” NCT02256150 ↗ |
| Target | GMPS | “GMP synthase [glutamine-hydrolyzing] inhibitor” CHEMBL245019 ↗ |