drugset / Trial / NCT02257697

A Study to Evaluate the Efficacy and Safety of Mizoribine in the Treatment of Refractory Nephrotic Syndrome

NCT02257697

Phase 3 Completed 239 enrolled Asahi Kasei Therapeutics Corporation
RandomizedParallel-groupOpen-labelTreatment

Summary

To demonstrate that the treatment effect in refractory nephrotic syndrome of MZR is non-inferior to that of standard therapy CTX through analyzing overall remission rate after treatment.

Timeline

Start
2014-11
Primary completion
2018-11
Completion
2018-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cyclophosphamide Other / unclassified 0.5 g Intravenous
Comparator Cyclophosphamide Other / unclassified 1 g Intravenous
Subject Mizoribine Small molecule 150 mg Oral

Indications