drugset / Trial / NCT02257697
A Study to Evaluate the Efficacy and Safety of Mizoribine in the Treatment of Refractory Nephrotic Syndrome
RandomizedParallel-groupOpen-labelTreatment
Summary
To demonstrate that the treatment effect in refractory nephrotic syndrome of MZR is non-inferior to that of standard therapy CTX through analyzing overall remission rate after treatment.
Timeline
- Start
- 2014-11
- Primary completion
- 2018-11
- Completion
- 2018-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cyclophosphamide | Other / unclassified | 0.5 g | Intravenous |
| Comparator | Cyclophosphamide | Other / unclassified | 1 g | Intravenous |
| Subject | Mizoribine | Small molecule | 150 mg | Oral |