Drugs / Xylitol
Xylitol
also known as
C-xylidex cr 16055 · E-967 · Eutrit · Fluorette · INS NO.967 · INS-967 · Kannit · Klinit · +11 more
Trials 22 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 02 trials | ||||||
| Phase 0 | NCT06799039 | Sep 2026 → Sep 2030 expected | Clostridium difficile colitis | Brigham and Women's Hospital | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT03877705 | Sep 2019 → Sep 2020 | — | Cairo University | Unknown | No outcome recorded |
| Phase 12 trials | ||||||
| Phase 1 | NCT05852587 | Aug 2026 → Jan 2032 expected | Clostridium difficile colitis | Brigham and Women's Hospital | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT03996044 | Jan → Jun 2021 | — | University of Nove de Julho | Completed | No outcome recorded |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT00928135 | Jan 2013 → Apr 2018 | cystic fibrosis | Joseph Zabner | Completed | No outcome recorded |
| Phase 1/2 | NCT01355796 | May 2011 → Feb 2015 | cystic fibrosis | Joseph Zabner | Completed | No outcome recorded |
| Phase 25 trials | ||||||
| Phase 2 | NCT04086212 | Oct 2019 → Dec 2022 | end stage renal failure | Iperboreal Pharma Srl | Withdrawn | No outcome recorded |
| Phase 2 | NCT04117477 | Sep 2019 → Mar 2021 | disease related to hematopoietic stem cell transplant | Children's Hospital Medical Center, Cincinnati | Terminated | No outcome recorded |
| Phase 2 | NCT04001036 | Sep 2019 → Aug 2022 | end stage renal failure | Iperboreal Pharma Srl | Terminated | No outcome recorded |
| Phase 2 | NCT01700725 | Oct 2012 → Jun 2016 | chronic rhinosinusitis, persian gulf syndrome | University of Wisconsin, Madison | Completed | No outcome recorded |
| Phase 2 | NCT00858182 | May 2009 → Oct 2012 | end stage renal failure | Iperboreal Pharma Srl | Withdrawn | No outcome recorded |
| Phase 2/33 trials | ||||||
| Phase 2/3 | NCT03229551 | Mar → Jul 2018 | chronic rhinosinusitis | Ochsner Health System | Completed | No outcome recorded |
| Phase 2/3 | NCT02950311 | Nov 2017 | otitis media with effusion | Duke University | Withdrawn | No outcome recorded |
| Phase 2/3 | NCT04399161 | Feb → Dec 2017 | — | Dr. Krupa NC | Completed | No outcome recorded |
| Phase 34 trials | ||||||
| Phase 3 | NCT04854486 | Dec 2021 → Mar 2022 | COVID-19 | Larkin Community Hospital | Withdrawn | No outcome recorded |
| Phase 3 | NCT04610801 | Dec 2021 → Jun 2022 | COVID-19 | Larkin Community Hospital | Withdrawn | No outcome recorded |
| Phase 3 | NCT04858620 | Aug 2020 → Aug 2021 | COVID-19 | Larkin Community Hospital | Withdrawn | No outcome recorded |
| Phase 3 | NCT01044030 | Feb 2010 → Jun 2012 | otitis media | Boston Children's Hospital | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT02036151 | Feb 2009 → Jul 2011 | dental caries | King Abdulaziz University | Completed | No outcome recorded |
| Phase not applicable3 trials | ||||||
| — | NCT05585476 | Oct 2025 → Jun 2026 overdue | female breast carcinoma, female reproductive system disorder | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | Not yet recruiting | No outcome recorded |
| — | NCT06108921 | Feb 2020 → Feb 2023 | chronic rhinosinusitis | Taichung Veterans General Hospital | Completed | No outcome recorded |
| — | NCT00924404 | May 2009 → Aug 2014 | chronic rhinosinusitis | University of Iowa | Completed | No outcome recorded |
Also used as a comparator or background therapy in 4 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT03394729 Comparator | Sep 2017 → Oct 2020 | — | Federal University of Rio de Janeiro | Completed | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT07210697 Comparator | Oct 2025 → Mar 2026 overdue | — | West Virginia University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT05342272 Comparator | Sep 2017 → Jan 2018 | — | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT00066040 Background | Jan 2001 → Jan 2006 | dental caries | New York University | Completed | No outcome recorded |
Evidence & citations 22 cited values
Every value below carries the sentence it was read from. 27 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Xylitol | “Instillation of a PD solution containing xylitol (1.5%), L-carnitine (0.1%) and glucose (0.5%) for the nocturnal exchange in CAPD treated patients.” NCT00858182 ↗25“Group 3: probiotic capsule containing Lactobacillus salivarius WB21 (6.7 x 108 CFU) and xylitol (280mg), 3 times a day after meals, for 14 days;” PMID 38954692 ↗ Jul 2024 “It is a moisturizing and regenerating gel whose active ingredients are olive oil, trimethylglycine and xylitol.” NCT05585476 ↗ “Xylitol plus Grapefruit Seed Extract (Xlear) nasal spray, 2 puffs per nosetrils, every 6 hours” NCT04610801 ↗ “Xylitol plus Grapefruit Seed Extract (Xlear) nasal spray, 2 puffs per nostrils, every 6 hours” NCT04858620 ↗ “Dissolving xylitol chewable tablets” NCT03877705 ↗ “GSE and Xylitol” NCT04854486 ↗ “Xylitol tablet” NCT03394729 ↗ |
| Known as | C-xylidex cr 16055 | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | E-967 | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Eutrit | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Fluorette | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | INS NO.967 | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | INS-967 | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Kannit | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Klinit | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Kylit | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | NSC-25283 | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Torch | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Xylitab 300 | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Xylite | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Xylite (sugar) | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Xylitol cm 90 | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Xylitol, d- | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Xyliton | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Xylo-pentane-1,2,3,4,5-pentol | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Known as | Xylo-pentitol | ChEMBL registry synonym — accepted as the source's own label CHEMBL96783 ↗ |
| Modality | Small molecule | “Xylitol is a sugar alcohol and considered a GRAS substance by the FDA.” NCT05852587 ↗ |
| Route | Other | “Instillation of a PD solution containing xylitol (1.5%), L-carnitine (0.1%) and glucose (0.5%) for the nocturnal exchange in CAPD treated patients.” NCT00858182 ↗ |