drugset / Trial / NCT00858182
Study of Safety and Efficacy on New Peritoneal Dialysis Solutions
Non-randomizedParallel-groupOpen-labelTreatment
Summary
A major challenge of peritoneal dialysis (PD) therapy is the development of glucose-sparing strategies able to provide an efficacious ultrafiltration (UF) profile. Study hypothesis is to evaluate the possibility to formulate PD solutions containing xylitol and L-carnitine as osmotic agents to partially replace glucose.
Timeline
- Start
- 2009-05
- Primary completion
- 2012-10
- Completion
- 2013-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Glucose | Unknown | 0.5 % | Other |
| Subject | L-carnitine | Other / unclassified | 0.1 % | Other |
| Subject | Xylitol | Small molecule | 0.6 % | Other |
| Subject | Xylitol | Small molecule | 1.5 % | Other |