Drugs / streptomycin
streptomycin
also known as
Agrimycin 17 · Agrimycin sulfate · Ambistryn s · Chemform · Estreptomicina · Gerox · NSC-14083 · NSC-757316 · +9 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | STREPTOMYCIN SULFATE | — | 1946-02-18 | fda.gov ↗ |
Trials 8 · a red edge is where a trial was stopped
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT02128308 | Nov → Dec 2013 | — | Seoul National University Hospital | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT00004689 | Jan 1991 → Sep 1998 | Mycobacterium avium complex disease | National Jewish Health | Completed | No outcome recorded |
| Phase 2/32 trials | ||||||
| Phase 2/3 | NCT00321178 | May 2006 → Jan 2008 | Buruli ulcer disease | University Medical Center Groningen | Completed | No outcome recorded |
| Phase 2/3 | NCT00128466 | Aug 2004 → Feb 2007 | plague | Centers for Disease Control and Prevention | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT04110340 | Feb 2020 → Apr 2024 | bubonic plague, pneumonic plague | University of Oxford | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT03237182 | Jun 2017 → Dec 2022 | multidrug-resistant tuberculosis | Centre for the AIDS Programme of Research in South Africa | Terminated | No outcome recorded |
| Phase not applicable2 trials | ||||||
| — | NCT00004444 | Nov 1994 → Jan 2001 | pulmonary tuberculosis | FDA Office of Orphan Products Development | Completed | No outcome recorded |
| — | NCT00000796 | ? → Oct 1998 | HIV infectious disease, pulmonary tuberculosis | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
Also used as a comparator or background therapy in 5 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT02099240 Comparator | Mar 2014 → Nov 2018 | osteomyelitis | University of Louisville | Terminated | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT02365623 Background | Feb 2015 → Nov 2018 | multidrug-resistant tuberculosis | Janssen Pharmaceutical K.K. | Completed | No outcome recorded |
| Phase 2/32 trials | ||||||
| Phase 2/3 | NCT01659437 Comparator | Dec 2012 → Dec 2017 | Buruli ulcer disease | University Medical Center Groningen | Completed | No outcome recorded |
| Phase 2/3 | NCT00495326 Background | Dec 2007 → Apr 2011 | AIDS, tuberculosis | French National Agency for Research on AIDS and Viral Hepatitis | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT02331823 Comparator | Jun 2013 → Dec 2015 | pulmonary tuberculosis | Shanghai Pulmonary Hospital, Shanghai, China | Unknown | No outcome recorded |
Evidence & citations 20 cited values
Every value below carries the sentence it was read from. 14 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Streptomycin | “Eligible patients were randomly assigned to receive intramuscular streptomycin (15 mg/kg once daily) and oral rifampicin (10 mg/kg once daily) for 8 weeks (8-week streptomycin...” PMID 20137805 ↗ Feb 201012“anti-bacterial tuberculosis drugs (pyrazinamide [PZA], ethambutol [EB, EMB], streptomycin [SM], kanamycin [KM, KAN], enviomycin [EVM], ethionamide [TH], cycloserine [CS],...” NCT02365623 ↗ “Patients with meningitis will receive Streptomycin instead of E during intensive phase.” NCT00495326 ↗ “kanamycin, streptomycin, ethionamide, prothionamide” NCT03237182 ↗ “Streptomycin” NCT02099240 ↗ |
| Known as | Agrimycin 17 | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Agrimycin sulfate | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Ambistryn s | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Chemform | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Estreptomicina | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Gerox | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | NSC-14083 | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | NSC-757316 | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Strepcen | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Streptomycin (as sulfate) | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Streptomycin sesquisulfate | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | STREPTOMYCIN SULFATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Streptomycin sulfate (2:3) (salt) | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Streptomycin sulphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Streptomycine | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Streptomycini sulfas | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Known as | Vetstrep | ChEMBL registry synonym — accepted as the source's own label CHEMBL372795 ↗ |
| Modality | Other / unclassified | “an aminoglycoside (streptomycin or gentamicin)” NCT04110340 ↗ |
| Route | Intramuscular | “Patients in arm III receive streptomycin intramuscularly once a day for 3 days.” NCT00004444 ↗ |