Phase 1 53 trials
Phase 1
NCT03400306
Nov 2021
ovarian cancer
AbbVie
Withdrawn
No outcome recorded
Phase 1
NCT02831179
Dec 2017 → Feb 2019
VIPoma , Zollinger-Ellison syndrome , adrenal cortex carcinoma , cutaneous neuroendocrine carcinoma +10
Vanderbilt-Ingram Cancer Center
Withdrawn
No outcome recorded
Phase 1
NCT02723864
Aug 2017 → Dec 2020
neoplasm
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT02631733
May 2017 → Nov 2019
cancer
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT03061188
May 2017 → Mar 2018
T-cell non-Hodgkin lymphoma , high grade malignant neoplasm , mantle cell lymphoma
Northwestern University
Completed
No outcome recorded
Phase 1
NCT02944396
Dec 2016 → Oct 2019
non-small cell lung carcinoma
AbbVie
Completed
No outcome recorded
Phase 1
NCT03227016
Oct 2016 → May 2021
small cell lung carcinoma
Central European Society for Anticancer Drug Research
Unknown
No outcome recorded
Phase 1
NCT02483104
Jul 2015 → Mar 2016
ovarian cancer
AbbVie
Completed
No outcome recorded
Phase 1
NCT02210663
Jul 2014 → Jan 2016
cancer
AbbVie
Completed
No outcome recorded
Phase 1
NCT02033551
Dec 2013 → Sep 2016
breast cancer , colorectal cancer , gastric cancer , lung cancer +1
AbbVie
Completed
No outcome recorded
Phase 1
NCT02009631
Nov 2013 → Dec 2014
breast cancer , colorectal cancer , gastric cancer , lung cancer +1
AbbVie
Completed
No outcome recorded
Phase 1
NCT01908478
Oct 2013 → Jul 2017
malignant pancreatic neoplasm
Cedars-Sinai Medical Center
Completed
No outcome recorded
Phase 1
NCT01618357
Jul 2013 → Sep 2023
breast cancer
Richard Zellars
Completed
No outcome recorded
Phase 1
NCT01853306
Mar 2013 → May 2017
hereditary breast carcinoma , hereditary neoplastic syndrome , ovarian serous adenocarcinoma
AbbVie
Completed
No outcome recorded
Phase 1
NCT01749397
Dec 2012 → Oct 2017
fallopian tube cancer , primary peritoneal carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01589419
Jun 2012 → Jan 2015
—
AbbVie
Completed
No outcome recorded
Phase 1
NCT01617928
May 2012 → Jul 2013
cancer
AbbVie
Completed
No outcome recorded
Phase 1
NCT01477489
Jan 2012 → Oct 2014
breast cancer
University of Michigan Rogel Cancer Center
Completed
No outcome recorded
Phase 1
NCT01434316
Nov 2011 → Mar 2023 overdue
cancer
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1
NCT01459380
Oct 2011 → Jun 2016
fallopian tube carcinoma , ovarian clear cell cystadenocarcinoma , ovarian endometrioid adenocarcinoma , ovarian seromucinous carcinoma +3
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01495351
Oct 2011 → Feb 2015
plasma cell myeloma
AHS Cancer Control Alberta
Completed
No outcome recorded
Phase 1
NCT01419548
Jul → Nov 2011
neoplasm
National Cancer Institute (NCI)
Withdrawn
No outcome recorded
Phase 1
NCT01366144
Jun 2011 → Nov 2017 overdue
breast carcinoma , cancer of unknown primary site , carcinoma of esophagus , endometrial carcinoma +9
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1
NCT01351909
May 2011 → Nov 2016 overdue
breast carcinoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1
NCT01281852
Mar 2011 → Feb 2017
cervical adenosquamous carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01264432
Jan 2011 → Nov 2016
fallopian tube carcinoma , ovarian carcinoma , peritoneal carcinomatosis , primary peritoneal carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01282333
Jan 2011 → Feb 2013
bladder transitional cell carcinoma , extrahepatic bile duct carcinoma , gallbladder carcinoma , non-small cell lung carcinoma +2
National Cancer Institute (NCI)
Terminated
No outcome recorded
Phase 1
NCT01281150
Jan 2011 → Apr 2015
estrogen-receptor positive breast cancer , female breast carcinoma , male breast carcinoma , triple-negative breast carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01251874
Nov 2010 → Sep 2024 overdue
triple-negative breast carcinoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1
NCT01233505
Oct 2010 → Oct 2013
BRCA1-related cancer predisposition , BRCA2-related cancer predisposition , cancer of unknown primary site , female breast carcinoma +5
National Cancer Institute (NCI)
Terminated
No outcome recorded
Phase 1
NCT01104259
Jul 2010 → Feb 2015
BRCA1-related cancer predisposition , BRCA2-related cancer predisposition , male breast carcinoma , triple-negative breast carcinoma
University of Washington
Completed
No outcome recorded
Phase 1
NCT01139970
Jun 2010 → Apr 2014
B-cell adult acute lymphocytic leukemia , B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) , T-cell adult acute lymphocytic leukemia , acute myeloid leukemia and myelodysplastic syndromes related to alkylating agent +6
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01145430
Jun 2010 → May 2017
fallopian tube carcinoma , male breast carcinoma , ovarian carcinoma , primary peritoneal carcinoma +1
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01199224
Jun → Nov 2010
cancer
AbbVie
Completed
No outcome recorded
Phase 1
NCT01154426
May 2010 → Oct 2013
BRCA1-related cancer predisposition , BRCA2-related cancer predisposition , neoplasm
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01085422
Apr 2010 → Jun 2011
prostate cancer
AbbVie
Completed
No outcome recorded
Phase 1
NCT01123876
Mar 2010 → Jan 2015
gastric cancer
AbbVie
Completed
No outcome recorded
Phase 1
NCT01063816
Jan 2010 → Aug 2016
neoplasm
AbbVie
Completed
No outcome recorded
Phase 1
NCT00989651
Oct 2009 → Sep 2016
fallopian tube carcinosarcoma , fallopian tube clear cell adenocarcinoma , fallopian tube endometrioid adenocarcinoma , fallopian tube mucinous adenocarcinoma +11
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01017640
Oct 2009 → May 2016
neoplasm
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT00994071
Sep 2009 → Mar 2013
astrocytoma (excluding glioblastoma) , brain stem glioma , ependymoma , medulloblastoma +1
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT00770471
Jul 2009 → Mar 2012
central nervous system neoplasm
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Completed
No outcome recorded
Phase 1
NCT00946335
Jul 2009 → Oct 2011
atypical teratoid rhabdoid tumor , benign meningioma , childhood brain stem glioma , childhood central nervous system germ cell tumor +18
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT00892736
Apr 2009 → May 2017
BRCA1-related cancer predisposition , BRCA2-related cancer predisposition , basal-like breast carcinoma , fallopian tube carcinoma +4
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01445522
Dec 2008 → Jul 2012
lymphoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT00740805
Aug 2008 → Sep 2021 overdue
primary organ-specific lymphoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1
NCT00576654
Mar 2008 → Jan 2020
metastatic malignant neoplasm , triple-negative breast carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT00649207
Mar 2008 → Mar 2013
brain neoplasm , metastatic neoplasm
AbbVie
Completed
No outcome recorded
Phase 1
NCT00588991
Feb 2008 → Nov 2016
acquired polycythemia vera , acute megakaryoblastic leukemia in adult , acute myeloblastic leukemia with maturation , acute myeloblastic leukemia without maturation +13
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT00535119
Sep 2007 → Oct 2012
BRCA1-related cancer predisposition , BRCA2-related cancer predisposition , hereditary breast ovarian cancer syndrome , neoplasm
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT00553189
Aug 2007 → Feb 2008
cancer , lymphoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT00526617
Aug 2007 → Jun 2010
breast cancer , fallopian tube cancer , hepatocellular carcinoma , metastatic melanoma +2
AbbVie
Completed
No outcome recorded
Phase 1
NCT00387608
Jun 2006 → Feb 2008
cancer of unknown primary site , leukemia , lymphoma
National Institutes of Health Clinical Center (CC)
Completed
No outcome recorded
Show 43 more trials
Phase 1/2 12 trials
Phase 1/2
NCT02412371
Apr 2015 → Aug 2019
non-small cell lung carcinoma
AbbVie
Terminated
No outcome recorded
Phase 1/2
NCT02289690
Oct 2014 → Apr 2019
small cell lung carcinoma
AbbVie
Completed
No outcome recorded
Phase 1/2
NCT01690598
Nov 2012 → Jan 2015
ovarian carcinoma
Vejle Hospital
Completed
No outcome recorded
Phase 1/2
NCT01711541
Oct 2012 → Feb 2018
head and neck squamous cell carcinoma , oropharyngeal carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1/2
NCT01642251
Sep 2012 → Dec 2016
lung large cell carcinoma , small cell lung carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1/2
NCT01514201
Feb 2012 → Mar 2018
anaplastic astrocytoma , brain stem glioma , fibrillary astrocytoma , giant cell glioblastoma +2
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1/2
NCT01472783
Nov 2011 → Jan 2016
malignant epithelial tumor of ovary
Vejle Hospital
Completed
No outcome recorded
Phase 1/2
NCT01326702
Jul 2011 → Apr 2015
B-cell adult acute lymphocytic leukemia , Burkitt lymphoma , Hodgkin's lymphoma, mixed cellularity , MALT lymphoma +19
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1/2
NCT01386385
Jun 2011 → May 2019 overdue
lung large cell carcinoma , minimally invasive lung adenocarcinoma , squamous cell lung carcinoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1/2
NCT01489865
Jan 2011 → Dec 2018
malignant pancreatic neoplasm
Georgetown University
Completed
No outcome recorded
Phase 1/2
NCT01026493
Jul 2010 → May 2014
central nervous system neoplasm
Radiation Therapy Oncology Group
Completed
No outcome recorded
Phase 1/2
NCT01012817
Nov 2009 → Jan 2019 overdue
fallopian tube carcinoma , metastatic malignant neoplasm , ovarian carcinoma , primary peritoneal carcinoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Show 2 more trials
Phase 2 27 trials
Phase 2
NCT03044795
Nov 2019 → Nov 2020
cancer
University Medical Center Groningen
Withdrawn
No outcome recorded
Phase 2
NCT03581292
Nov 2018 → Mar 2023 overdue
anaplastic astrocytoma , glioblastoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT03289910
Sep 2018 → May 2023 overdue
acquired polycythemia vera , acute myeloid leukemia , atypical chronic myeloid leukemia, BCR-ABL1 negative , chronic myelomonocytic leukemia +2
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT03032614
Sep 2017 → Mar 2019
BRCA1-related cancer predisposition , BRCA2-related cancer predisposition , breast cancer , ovarian cancer
The University of Texas Health Science Center at San Antonio
Withdrawn
No outcome recorded
Phase 2
NCT02921256
Jan 2017 → Apr 2020
rectum adenocarcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT02890355
Oct 2016 → May 2019
pancreatic adenocarcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT02595905
Sep 2016 → Jan 2025
hereditary breast carcinoma , metastatic malignant neoplasm in the brain , triple-negative breast carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT02860819
Aug 2016 → Nov 2020
testicular germ cell tumor
National Cancer Institute, Slovakia
Completed
No outcome recorded
Phase 2
NCT02305758
Dec 2014 → Sep 2017
colorectal cancer
AbbVie
Completed
No outcome recorded
Phase 2
NCT01827384
Jan 2014 → Jun 2021
cancer
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01818063
Apr 2013 → Mar 2015
triple-negative breast carcinoma
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Completed
No outcome recorded
Phase 2
NCT01657799
Oct 2012 → Jan 2015
non-small cell lung carcinoma
AbbVie
Completed
No outcome recorded
Phase 2
NCT01638546
Jul 2012 → Jan 2017 overdue
small cell lung carcinoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT01585805
May 2012 → Dec 2024 overdue
pancreatic adenocarcinoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT01540565
Apr 2012 → Jan 2018
BRCA1-related cancer predisposition , BRCA2-related cancer predisposition , fallopian tube carcinoma , ovarian carcinoma +1
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01576172
Mar 2012 → Oct 2019
castration-resistant prostate carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01560104
Feb 2012 → Sep 2014
non-small cell lung carcinoma
AbbVie
Completed
No outcome recorded
Phase 2
NCT01506609
Jan 2012 → Dec 2018
breast cancer
AbbVie
Completed
No outcome recorded
Phase 2
NCT01266447
Feb 2011 → Jan 2016
cervical adenosquamous carcinoma , cervical small cell carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01306032
Jan 2011 → Dec 2014
fallopian tube cancer , ovarian cancer , primary peritoneal carcinoma , serous adenocarcinoma +1
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01205828
Aug 2010 → Oct 2014
hepatocellular carcinoma
Georgetown University
Terminated
No outcome recorded
Phase 2
NCT01193140
Jul 2010 → Nov 2011
—
Abbott
Completed
No outcome recorded
Phase 2
NCT01149083
Jun 2010 → Sep 2024
female breast carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01042379
Mar 2010 → Dec 2030 expected
HER2 positive breast carcinoma , angiosarcoma , female breast carcinoma , hormone receptor-positive breast cancer +1
QuantumLeap Healthcare Collaborative
Recruiting
No outcome recorded
Phase 2
NCT01113957
Mar 2010 → Jun 2013
ovarian cancer
AbbVie
Completed
No outcome recorded
Phase 2
NCT01009788
Nov 2009 → Sep 2012
BRCA1-related cancer predisposition , BRCA2-related cancer predisposition , breast cancer
Steven J Isakoff, MD, PhD
Completed
No outcome recorded
Phase 2
NCT01051596
Sep 2009 → Jun 2013
colorectal cancer
Georgetown University
Completed
No outcome recorded
Show 17 more trials
Phase 2/3 1 trial
Phase 2/3
NCT02152982
Dec 2014 → Dec 2021 overdue
gliosarcoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 3 4 trials
Phase 3
NCT02470585
Jul 2015 → May 2019
ovarian cancer
AbbVie
Terminated
No outcome recorded
Phase 3
NCT02264990
Sep 2014 → Nov 2019
non-small cell lung carcinoma
AbbVie
Completed
No outcome recorded
Phase 3
NCT02106546
Apr 2014 → Jan 2017
non-small cell squamous lung carcinoma
AbbVie
Completed
No outcome recorded
Phase 3
NCT02163694
Apr 2014 → Apr 2019
breast cancer
AbbVie
Completed
No outcome recorded
Phase not applicable 1 trial
—
NCT02158507
Sep 2014 → Jul 2021
triple-negative breast carcinoma
University of Alabama at Birmingham
Completed
No outcome recorded
Phase not stated 1 trial
—
NCT02985658
—
hereditary breast carcinoma , triple-negative breast carcinoma
University of Washington
No longer available
No outcome recorded