drugset / Trial / NCT00535119

Veliparib, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Cancer

NCT00535119

Phase 1 Completed 107 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase I trial is studying the side effects and best dose of veliparib when given together with carboplatin and paclitaxel in treating patients with advanced solid cancer. Veliparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving veliparib together with carboplatin and paclitaxel may help kill more tumor cells.

Timeline

Start
2007-09
Primary completion
2012-10
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule Intravenous
Subject Paclitaxel Small molecule Intravenous
Subject Veliparib Small molecule Oral