Drugs / Tripterygium wilfordii Hook F
last change Dec 2022 re-read 2 minutes ago

Tripterygium wilfordii Hook F

also known as TwHF

Traditional medicine (herbal / TCM)

Developed for
rheumatoid arthritis · lupus nephritis
Investigated by
Guang'anmen Hospital of China Academy of Chinese Medical Sciences · Peking Union Medical College Hospital

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2/35 trials
Phase 2/3 NCT04136262 Nov 2019 → Dec 2022 rheumatoid arthritis Guang'anmen Hospital of China Academy of Chinese Medical Sciences Unknown No outcome recorded
Phase 2/3 NCT03324412 Oct 2017 → May 2019 rheumatoid arthritis Guang'anmen Hospital of China Academy of Chinese Medical Sciences Unknown No outcome recorded
Phase 2/3 NCT03337815 Oct 2017 → Mar 2019 rheumatoid arthritis Guang'anmen Hospital of China Academy of Chinese Medical Sciences Unknown No outcome recorded
Phase 2/3 NCT01646736 Jul 2012 → Jul 2013 lupus nephritis Peking Union Medical College Hospital Unknown No outcome recorded
Phase 2/3 NCT01613079 May 2012 → Jun 2013 rheumatoid arthritis Peking Union Medical College Hospital Completed No outcome recorded
Phase not applicable1 trial
NCT02818361 Apr 2012 → Mar 2013 rheumatoid arthritis Guang'anmen Hospital of China Academy of Chinese Medical Sciences Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as Tripterygium wilfordii Hook F “a hospital-compounded gel preparation of Tripterygium wilfordii Hook F (TwHF)” PMID 28870177 Sep 2017
5

Tripterygium wilfordii Hook F(TwHF):20mg, 3 times a day, oral, for 24 weeks.” NCT03324412

Tripterygium wilfordii Hook F(TwHF):20mg,3 times a day, oral, for 24 weeks.” NCT03337815

NCT01613079

NCT04136262

NCT01646736

Known as TwHF “BACKGROUND: Tripterygium wilfordii Hook F (TwHF) alone or in combination with methotrexate (MTX) has been shown to be more effective than MTX monotherapy” PMID 29636089 Apr 2018
3

“a hospital-compounded gel preparation of Tripterygium wilfordii Hook F (TwHF)” PMID 28870177 Sep 2017

“Tripterygium wilfordii Hook F(TwHF):20mg, 3 times a day, oral, for 24 weeks.” NCT03324412

“Tripterygium wilfordii Hook F(TwHF):20mg,3 times a day, oral, for 24 weeks.” NCT03337815

Modality Traditional medicine (herbal / TCM) “Chinese herb medicine therapy” PMID 28870177 Sep 2017
Route Oral Oral T2(Tripterygium wilfordii Hook F) 20mg thrice daily for 24 weeks.” NCT01613079