drugset / Trial / NCT01646736

Efficacy and Safety of Tripterygium Wilfordii in Patients With Lupus Nephritis

NCT01646736

Phase 2/3 Unknown 130 enrolled Peking Union Medical College Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

Evaluation the clinical efficacy and safety profile of glucocorticosteroid combined with oral T2 (chloroform/methanol extract of Tripterygium wilfordii Hook F) in the treatment of patients with lupus nephritis. Open-labeled, randomized, prospective multi-center clinical trial. Observation period of 24 weeks.

Timeline

Start
2012-07
Primary completion
2013-07
Completion
2013-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cyclophosphamide Other / unclassified Intravenous
Subject Tripterygium wilfordii Hook F Traditional medicine (herbal / TCM) 20 mg Oral
Background Prednisone Other / unclassified 7.5 mg

Indications