Drugs / Lactobacillus acidophilus
last change May 2026 re-read 2 minutes ago

Lactobacillus acidophilus

Other / unclassified

Developed for
aphthous stomatitis · atopic eczema · autoimmune thrombocytopenia · bacterial vaginosis · brain injury · cervical lymphadenitis · dry eye syndrome · epilepsy
+15 more · hyperlipidemia · infectious disease with sepsis · irritable bowel syndrome · necrotizing enterocolitis · periodic fever syndrome · pharyngitis · postmenopausal atrophic vaginitis · ulcerative colitis · anemia · chronic kidney disease · colorectal cancer · Helicobacter pylori infectious disease · infectious disorder of the nervous system · nosocomial infection · seasonal allergic rhinitis
Investigated by
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · B.P. Koirala Institute of Health Sciences · Connecticut Children's Medical Center · DuPont Nutrition and Health · Eastern Mediterranean University · Forest Laboratories
+16 more · Hvidovre University Hospital · Instituto de Investigación Hospital Universitario La Paz · International Brain Research Foundation · Jinan Central Hospital · Medinova AG · Mohsen Pourazizi · Nepal Health Research Council · Novonesis · Qianfoshan Hospital · Qingdao University · Shandong University · Tanta University · Tel-Aviv Sourasky Medical Center · The Second Hospital of Shandong University · University of Brescia · Yantai Yuhuangding Hospital

Trials 13 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06793514 Feb → May 2025 overdue dry eye syndrome Mohsen Pourazizi Not yet recruiting No outcome recorded
Phase 1 NCT01370551 Apr 2011 → Jul 2012 postmenopausal atrophic vaginitis Medinova AG Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02696512 Mar 2016 → Mar 2017 brain injury International Brain Research Foundation Unknown No outcome recorded
Phase 25 trials
Phase 2 NCT05539287 Sep 2022 → Aug 2024 epilepsy Tanta University Completed No outcome recorded
Phase 2 NCT03033199 Jan 2017 → Feb 2018 autoimmune thrombocytopenia Shandong University Unknown No outcome recorded
Phase 2 NCT02535962 Oct 2016 → Sep 2017 aphthous stomatitis, cervical lymphadenitis, periodic fever syndrome, pharyngitis Connecticut Children's Medical Center Withdrawn No outcome recorded
Phase 2 NCT02307383 Oct 2014 → Oct 2015 Instituto de Investigación Hospital Universitario La Paz Unknown No outcome recorded
Phase 2 NCT00268164 Jun 2004 → Mar 2007 ulcerative colitis Hvidovre University Hospital Terminated No outcome recorded
Phase 31 trial
Phase 3 NCT01358708 Jun 2010 → Sep 2011 irritable bowel syndrome Forest Laboratories Terminated No outcome recorded
Phase 41 trial
Phase 4 NCT01558388 Sep 2009 → Dec 2012 bacterial vaginosis University of Brescia Unknown No outcome recorded
Phase not applicable3 trials
NCT04706559 Jan → Sep 2021 atopic eczema B.P. Koirala Institute of Health Sciences Completed No outcome recorded
NCT04701775 Sep 2018 → Feb 2019 hyperlipidemia Eastern Mediterranean University Completed No outcome recorded
NCT00835874 Jun 2007 → Jul 2009 infectious disease with sepsis, necrotizing enterocolitis Tel-Aviv Sourasky Medical Center Terminated No outcome recorded
Also used as a comparator or background therapy in 10 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT00746226 Comparator Mar → Jun 2006 seasonal allergic rhinitis Danisco Completed No outcome recorded
Phase 21 trial
Phase 2 NCT07293910 Comparator Feb → Dec 2026 expected Helicobacter pylori infectious disease Tanta University Recruiting No outcome recorded
Phase 32 trials
Phase 3 NCT07296146 Comparator Dec 2025 → Mar 2026 overdue anemia, chronic kidney disease Badr University Not yet recruiting No outcome recorded
Phase 3 NCT01340469 Comparator Jan 2005 → Mar 2008 necrotizing enterocolitis, nosocomial infection King Chulalongkorn Memorial Hospital Completed No outcome recorded
Phase 43 trials
Phase 4 NCT07144475 Comparator Jan → Nov 2024 colorectal cancer Dharmais National Cancer Center Hospital Completed No outcome recorded
Phase 4 NCT06151392 Comparator Jul 2023 → Dec 2025 overdue infectious disorder of the nervous system Ain Shams University Recruiting No outcome recorded
Phase 4 NCT04053790 Comparator Jan 2019 → Jan 2023 irritable bowel syndrome Hospital General de Mexico Completed No outcome recorded
Phase not applicable3 trials
NCT05674864 Comparator Jan → Aug 2023 Helicobacter pylori infectious disease Tanta University Unknown No outcome recorded
NCT00256022 Comparator Jul → Dec 2007 Melbourne Health Withdrawn No outcome recorded
NCT00256087 Comparator Jan 2005 → Jan 2010 Melbourne Health Completed No outcome recorded

Evidence & citations 15 cited values

Every value below carries the sentence it was read from. 25 sources stand behind the page.

FieldValueCited text
Known as Lactobacillus acidophilus “The experimental group will receive the oral probiotics (Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus acidophilus, Lactobacillus bulgaricus, Bifidobacterium...” NCT06793514
18

“probiotic capsules containing three viable and freezedried strains-Lactobacillus acidophilus,Lactobacillus casei, and Bifidobacterium bifidum:2 capsules, bid x 4 weeks for one...” NCT03033199

“Daily enteral probiotic supplementation (live Lactobacillus acidophilus and Bifidobacterium infantis) at a dose of 2.5 x 108 CFU of each strain once a day.” NCT01340469

“The second active treatment group will receive enteral feeding (with fibre) plus the probiotic Lactobacillus acidophilus included in the feeding regime.” NCT00256087

“Mothers were assigned to supplementation with Lactobacillus acidophilus and Bifidobacteria lactis 2 × 10(E) [DOSAGE ERROR CORRECTED] CFU/d or to placebo” PMID 23934538 Aug 2013

Lactobacillus acidophilus, 1 x 109 UFC and Lactobacillus Biphidus 1 x 109 UFC, (Infloran Berna), 2 tablets by mouth, three times a day for 21 days.” NCT02307383

“Two different lactobacillus strains will be assessed in the study: Lactobacillus Acidophilus and Lactobacillus Fermentum.” NCT00256022

“same antiepileptic regimen plus a daily probiotic (Lactobacillus acidophilus) supplement.” PMID 41693686 Mar 2026

Lactobacillus acidophilus (LA5) and Bifidobacterium animalis subsp. lactis (BB12)” NCT00268164

“Ultra-low-dose estriol and Lactobacillus acidophilus vaginal tablets” PMID 24718774 Apr 2014

“EPO (4000 IU) + Probiotic (Lactobacillus acidophilus, 5 billion)” NCT07296146

Lactobacillus acidophilusNCT07293910

NCT01558388

NCT00746226

NCT02535962

NCT07144475

NCT04701775

NCT04706559

NCT05674864

Known as Acidophilus “Battery of nutraceuticals provided through a 12-week schedule including: Acidophilus, Alpha-Lipoic Acid, Acetyl L-Carnitine,” NCT02696512
Known as Bacillus acidophilus whole ChEMBL registry synonym — accepted as the source's own label CHEMBL2109070
Known as Bacterium acidophilum whole ChEMBL registry synonym — accepted as the source's own label CHEMBL2109070
Known as Gynatren ChEMBL registry synonym — accepted as the source's own label CHEMBL2109070
Known as La-5 “A randomised double-blind placebo-controlled trial with Lactobacillus acidophilus La-5 and Bifidobacterium animalis subsp. lactis BB-12 for maintenance of remission in...” PMID 21453880 Jan 2011
1

“Lactobacillus acidophilus (LA5) and Bifidobacterium animalis subsp. lactis (BB12)” NCT00268164

Known as Lacteol Lacteol® is a lactobacillus product used for adjunctive and symptomatic treatment of diarrhea.” NCT01358708
1

NCT01358708

Known as Lactobacillus acidophilus component of lactinex ChEMBL registry synonym — accepted as the source's own label CHEMBL2109070
Known as Lactobacillus acidophilus whole ChEMBL registry synonym — accepted as the source's own label CHEMBL2109070
Known as Lactobacillus LB “Lacteol fort ® Sachets manufactured by Rameda contains Lactobacillus LB corresponding to lactobacillus delbruekii and lactobacillus fermentum 10 billion units per sachet.” NCT06151392
1

NCT04053790

Known as Lactobacterium acidophilum whole ChEMBL registry synonym — accepted as the source's own label CHEMBL2109070
Known as Probiotic “EPO (4000 IU) + Probiotic (Lactobacillus acidophilus, 5 billion)” NCT07296146
Known as Thermobacterium intestinale whole ChEMBL registry synonym — accepted as the source's own label CHEMBL2109070
Modality Other / unclassified “pre-operative prophylactic probiotic Lactobacilli tablets” NCT00256022
Route Other “Two capsules containing Lactobacillus acidophilus (2x10 9 organisms per capsule) will be delivered via the feeding tube 12 hourly.” NCT00256087