drugset / Trial / NCT00746226

Probiotics for Birch Pollen Allergy

NCT00746226

Phase 1/2 Completed 47 enrolled Danisco
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Birch pollen allergy is one of the most common forms of respiratory allergy in the Nordic countries. Treatment consists of antihistamine use. Specific probiotic strains have been observed to modulate the immune system. Since the body has a common mucosal immune system; it was hypothesised that consumption of probiotics may affect also the respiratory mucosal immune response and hence affect respiratory allergy. Earlier studies with probiotics had been unable to show improvements in adults with pollen allergy. It was therefore hypothesised that children, who's immune system is not yet fully developed, might be better targets.

Timeline

Start
2006-03
Primary completion
2006-06
Completion
2007-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Lactobacillus Unknown
Comparator Lactobacillus acidophilus Other / unclassified