Drugs / nitroprusside
nitroprusside
Trials 7 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT06520982 | Sep 2024 → Jun 2027 expected | sympathetic nervous system disorder | University of Missouri-Columbia | Recruiting | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT03102736 | Feb 2017 → Jun 2019 | depressive disorder | Icahn School of Medicine at Mount Sinai | Completed | No outcome recorded |
| Phase 2 | NCT00535808 | Oct 2007 → Mar 2011 | — | University Hospital, Ghent | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT00128791 | Jan 2003 → Apr 2005 | myocardial infarction | Soroka University Medical Center | Terminated | No outcome recorded |
| Phase not applicable3 trials | ||||||
| — | NCT02001298 | Jun 2012 → Jul 2013 | hypotensive disorder | Jeju National University School of Medicine | Completed | No outcome recorded |
| — | NCT01125943 | Jun 2010 → Oct 2011 | cancer, hypertensive disorder | Radboud University Medical Center | Completed | No outcome recorded |
| — | NCT00240058 | Jul 2005 → Jun 2006 | hypertensive disorder | Crystal A. Gadegbeku | Completed | No outcome recorded |
Also used as a comparator or background therapy in 6 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT00748059 Background | Dec 1996 → Dec 2020 | autonomic nervous system disorder, disorder of catecholamine synthesis, orthostatic hypotension | Vanderbilt University Medical Center | Completed | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT00621816 Comparator | Jan 2009 → Jan 2011 | hypertensive disorder | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Completed | No outcome recorded |
| Phase 2 | NCT00135668 Comparator | Aug 2005 → Mar 2008 | hypotensive disorder | The Emmes Company, LLC | Completed | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT00590070 Comparator | Jan 2008 → Jun 2011 | myocardial infarction | Catholic University of the Sacred Heart | Completed | No outcome recorded |
| Phase not applicable2 trials | ||||||
| — | NCT00226096 Background | Nov 2005 → Sep 2007 | intracerebral hemorrhage | The George Institute | Completed | No outcome recorded |
| — | NCT00168519 Comparator | Oct 2002 → Apr 2009 | type 2 diabetes mellitus | Baker Heart Research Institute | Completed | No outcome recorded |
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 15 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | nitroprusside | “Then, a research medication, L-NMMA, which blocks NO in the blood vessel, will be dripped into the same artery followed by another medication nitroprusside, which gives back...” NCT00240058 ↗ |
| Known as | NTP | “The investigators hypothesized that nitroprusside (NTP) injected intracoronary immediately before angioplasty might prevent no-reflow and improve vessel flow and myocardial perfusion.” NCT00128791 ↗ |
| Known as | SNP | “PURPOSE: (1) To define the onset and offset of the blood-pressure-lowering effects of sodium nitroprusside (SNP) for use in developing instructions for dose titration in...” PMID 26217225 ↗ Jul 20151“Sodium nitroprusside (SNP) is a known NO donor” NCT00168519 ↗ |
| Known as | sodium nitroprusside | “co-administration of sodium nitroprusside, a nitric oxide donor, compared to placebo, would attenuate the antidepressant and dissociative effects of ketamine.” PMID 33522376 ↗ Feb 2021 |
| Action | Restore | “nitroprusside, which gives back NO, to restore normal forearm blood flow” NCT00240058 ↗ |
| Modality | Other / unclassified | “nitric oxide donor” NCT00168519 ↗ |
| Route | Other | “injected intracoronary immediately before angioplasty” NCT00128791 ↗ |