Drugs / Moxonidine
Moxonidine
also known as
BDF-5896 · BE-5895 · Brand name = Physiotens · Cynt · Fisiotens · LY-326869 · Moxonidina · MOXONIDINE HYDROCHLORIDE · +2 more
Small molecule targets NISCH via activation
Trials 15 · a red edge is where a trial was stopped
Also used as a comparator or background therapy in 4 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 31 trial | ||||||
| Phase 3 | NCT00244504 Comparator | Nov 2002 → Mar 2006 | heart disorder | University Hospital, Basel, Switzerland | Terminated | No outcome recorded |
| Phase 43 trials | ||||||
| Phase 4 | NCT01791699 Comparator | Aug 2012 → Nov 2013 | atrial fibrillation | Spyridon Deftereos | Completed | No outcome recorded |
| Phase 4 | NCT01504321 Comparator | May 2012 → May 2015 | polycystic ovary syndrome | Baker Heart and Diabetes Institute | Completed | No outcome recorded |
| Phase 4 | NCT01180231 Comparator | Sep 2010 → Sep 2014 | obesity disorder | Baker Heart and Diabetes Institute | Unknown | No outcome recorded |
Evidence & citations 16 cited values
Every value below carries the sentence it was read from. 21 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Moxonidine | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02355821 ↗ |
| Known as | BDF-5896 | ChEMBL registry synonym — accepted as the source's own label CHEMBL19236 ↗ |
| Known as | BE-5895 | ChEMBL registry synonym — accepted as the source's own label CHEMBL19236 ↗ |
| Known as | Brand name = Physiotens | “Brand name = Physiotens” NCT01360710 ↗ |
| Known as | Cynt | ChEMBL registry synonym — accepted as the source's own label CHEMBL19236 ↗ |
| Known as | Fisiotens | ChEMBL registry synonym — accepted as the source's own label CHEMBL19236 ↗ |
| Known as | LY-326869 | ChEMBL registry synonym — accepted as the source's own label CHEMBL19236 ↗ |
| Known as | Moxonidina | ChEMBL registry synonym — accepted as the source's own label CHEMBL19236 ↗ |
| Known as | MOXONIDINE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL19236 ↗ |
| Known as | Normatens | ChEMBL registry synonym — accepted as the source's own label CHEMBL19236 ↗ |
| Known as | Physiotens | ChEMBL registry synonym — accepted as the source's own label CHEMBL19236 ↗ |
| Action | Activate | “Nischarin agonist” CHEMBL19236 ↗ |
| Action | Inhibit | “the moxonidine molecule is known to reduce the AE protein activity.” NCT02355821 ↗ |
| Modality | Small molecule | — CHEMBL19236 ↗ |
| Route | Oral | “Small oral doses of moxonidine did not reduce the incidence of perioperative myocardial ischaemia” PMID 17968979 ↗ Dec 2007 |
| Target | NISCH | “Nischarin agonist” CHEMBL19236 ↗ |