Nigella sativa
Trials 10 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 23 trials | ||||||
| Phase 2 | NCT06422650 | Aug 2023 → Aug 2024 | hyperlipidemia | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Unknown | No outcome recorded |
| Phase 2 | NCT05693597 | Jan 2023 → Feb 2024 | radiodermatitis | German University in Cairo | Completed | No outcome recorded |
| Phase 2 | NCT01531062 | Sep → Dec 2011 | hyperlipidemia | Indonesia University | Completed | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT04553705 | Sep → Nov 2020 | COVID-19, immunodeficiency disease | Beni-Suef University | Completed | No outcome recorded |
| Phase 33 trials | ||||||
| Phase 3 | NCT04347382 | Apr → Aug 2020 | COVID-19 | Sohaib Ashraf | Completed | No outcome recorded |
| Phase 3 | NCT03925714 | Apr 2019 → Dec 2028 expected | — | Tanta University | Recruiting | No outcome recorded |
| Phase 3 | NCT01393054 | Jul → Oct 2011 | hypertensive disorder | Indonesia University | Unknown | No outcome recorded |
| Phase not applicable3 trials | ||||||
| — | NCT07447349 | Jan → Jun 2023 | gingivitis | Universitas Airlangga | Completed | No outcome recorded |
| — | NCT05494164 | Aug 2022 → May 2023 | chronic rhinosinusitis | Cairo University | Completed | No outcome recorded |
| — | NCT07055763 | Mar 2022 → Sep 2025 overdue | hypertensive disorder | Superior University | Active not recruiting | No outcome recorded |
Also used as a comparator or background therapy in 2 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT02816957 Comparator | Jun 2016 → Jun 2017 | beta-thalassemia major | Tanta University | Unknown | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT04989101 Comparator | Jun → Jul 2021 | acute respiratory distress syndrome | Hôpital Universitaire Sahloul | Completed | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 13 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Nigella sativa | “The clinical trial will be conducted to examine the effect of administering a daily dose of 100 mg Nigella sativa nasal oil drops for four weeks on selected outcomes which...” NCT05494164 ↗11“Nigella sativa as a promising intervention for metabolic and inflammatory disorders in obese prediabetic subjects: A comparative study of Nigella sativa versus both lifestyle...” PMID 34006388 ↗ May 2021 “Nigella sativa is a prophetic medicine remedy rich in pharmacological ingredients exerting anti-inflammatory and thrombocytosis effects that may improve the biochemistry of ITP...” PMID 41877935 ↗ Feb 2026 “Nigella sativa is an herbal medicine whose anti-inflammatory and antioxidant activities have been proven in several clinical trials.” NCT05693597 ↗ “This study will focus on the evaluation of the natural product Nigella Sativa in the fractalized form.” NCT04989101 ↗ “Nigella sativa or black seeds are traditional herbs used for years in Middle East and India.” NCT01531062 ↗ |
| Known as | Black Cumin | “Drug: Nigella Sativa / Black Cumin” NCT04347382 ↗ |
| Known as | black seed | “Participants in Group 1 (intervention group) will receive Nigella sativa (black seed) oil at a dosage of 0.5 ml, administered orally twice daily-once before breakfast and once...” NCT07055763 ↗ |
| Known as | black seed extract | “giving toothpaste with black seed extract (Nigella sativa) could inhibit inflammatory mediators” PMID 38744331 ↗ May 2024 |
| Known as | black seeds | “Nigella sativa or black seeds are traditional herbs used for years in Middle East and India.” NCT01531062 ↗ |
| Known as | N. sativa | “The researcher collaborated with Emeritus Professor in Pharmacognosy from the College of Pharmacy for the preparation of N. sativa nasal oil drops from Nigella sativa and Sesame seeds.” NCT05494164 ↗ |
| Action | Inhibit | “could inhibit inflammatory mediators” PMID 38744331 ↗ May 2024 |
| Modality | Traditional medicine (herbal / TCM) | “Nigella sativa or black seeds are traditional herbs” NCT01531062 ↗ |
| Route | Oral | “grinded nigella sativa seeds (taken orally added to foods or drinks)” PMID 41877935 ↗ Feb 2026 |