drugset

drugset / Trial / NCT03925714

Impact of P53 and SIRT1 in Type 2 Diabetes

NCT03925714 ↗

Phase 3 Recruiting 90 enrolled Tanta University

RandomizedParallel-groupOpen-labelPrevention

Summary

Investigating the impact of p53 and SIRT1 in the development of type 2 DM

Timeline

Start: 2019-04-01
Primary completion: 2028-12
Completion: 2028-12

Publications

Mostafa TM, Hegazy SK, Elnaidany SS, Shehabeldin WA, Sawan ES. Nigella sativa as a promising intervention for metabolic and inflammatory disorders in obese prediabetic subjects: A comparative study of Nigella sativa versus both lifestyle modification and metformin. J Diabetes Complications. 2021 Jul;35(7):107947. doi: 10.1016/j.jdiacomp.2021.107947. Epub 2021 May 8.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Metformin	Small molecule	500 mg	—
Subject	Nigella sativa	Traditional medicine (herbal / TCM)	450 mg	—

Indications

No indication recorded.