Drugs / indibulin
last change Aug 2018 re-read 2 minutes ago

indibulin

also known as D-24851 · Indibulina · Indibuline · ZIO-301

Small molecule

Developed for
cancer · breast cancer
Investigated by
Alaunos Therapeutics · Memorial Sloan Kettering Cancer Center

Trials 6 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT00591383 Jan 2008 → Jun 2013 cancer Alaunos Therapeutics Unknown No outcome recorded
Phase 1 NCT00591890 Oct 2007 → Jun 2008 Alaunos Therapeutics Completed No outcome recorded
Phase 1 NCT00591292 Jun 2007 → Jun 2013 cancer Alaunos Therapeutics Unknown No outcome recorded
Phase 1 NCT00591136 Apr 2003 → Sep 2008 cancer Alaunos Therapeutics Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT01113970 Mar 2010 → May 2013 breast cancer Alaunos Therapeutics Unknown No outcome recorded
Phase 1/2 NCT00726687 Jun 2008 → Jun 2013 cancer Alaunos Therapeutics Unknown No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as indibulin ClinicalTrials.gov intervention name — accepted as the source's own label NCT00591890
5

NCT01113970

NCT00591136

NCT00591383

NCT00591292

NCT00726687

Known as D-24851 ChEMBL registry synonym — accepted as the source's own label CHEMBL49642
Known as Indibulina ChEMBL registry synonym — accepted as the source's own label CHEMBL49642
Known as Indibuline ChEMBL registry synonym — accepted as the source's own label CHEMBL49642
Known as ZIO-301 ChEMBL registry synonym — accepted as the source's own label CHEMBL49642
Action Inhibit “Indibulin, a synthetic inhibitor of tubulin assembly, has shown promising anticancer activity with a minimal neurotoxicity in preclinical animal studies and in Phase I clinical...” PMID 30120268 Aug 2018
Modality Small molecule “Indibulin, a synthetic inhibitor of tubulin assembly” PMID 30120268 Aug 2018