Drugs / Paromomycin
Paromomycin
also known as
Paromomycin Sulfate · Aminosidin · aminosidine · Aminoxidin · ANTIBIOTIC 503-3 · ANTIBIOTIC SF 767B · Catenulin · Crestomycin · +28 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | HUMATIN | — | 1969-03-24 | fda.gov ↗ |
Trials 28 · a red edge is where a trial was stopped
Also used as a comparator or background therapy in 6 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT02099240 Comparator | Mar 2014 → Nov 2018 | osteomyelitis | University of Louisville | Terminated | No outcome recorded |
| Phase 23 trials | ||||||
| Phase 2 | NCT05957978 Comparator | Mar 2024 → Jun 2025 | visceral leishmaniasis | Drugs for Neglected Diseases | Completed | No outcome recorded |
| Phase 2 | NCT01083576 Comparator | Mar 2010 → Jun 2011 | cutaneous leishmaniasis | U.S. Army Medical Research and Development Command | Completed | No outcome recorded |
| Phase 2 | NCT01032382 Comparator | Jan 2010 → Mar 2011 | cutaneous leishmaniasis | U.S. Army Medical Research and Development Command | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT07463040 Comparator | Jan 2027 → Mar 2029 expected | cutaneous leishmaniasis | Institute of Tropical Medicine, Belgium | Not yet recruiting | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT00001128 Background | ? → Jun 2005 | HIV infectious disease, cryptosporidiosis | National Institute of Allergy and Infectious Diseases (NIAID) | Terminated | No outcome recorded |
Evidence & citations 39 cited values
Every value below carries the sentence it was read from. 38 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Paromomycin | “Assessment of Cutaneous Leishmaniasis Scar (Caused by Leishmania Major) for Cosmetic Outcome After Treatment With WR279396 (Paromomycin/Gentamicin Cream in Vehicle) Versus a No...” NCT00490230 ↗30“WR 279,396 is a topical antibiotic cream containing paromomycin and gentamicin that will be applied to each lesion once a day for 20 days and covered with a sterile gauze and...” NCT01494350 ↗ “The antibiotic paromomycin 15% in the same topical cream used in arm 1 will be applied to lesions daily and covered with a protective sterile gauze and tape dressing.” NCT00606580 ↗ “The active ingredients of WR279396 are two aminoglycosides - paromomycin sulphate (15%) and gentamicin sulphate (0.5%) - in a base (AQIC).” NCT01536795 ↗ “Topical application of WR 279,396 cream (15% paromomycin + 0.5% gentamicin)once daily for 20 days” NCT01140191 ↗ “WR 279,396 is a topical antibiotic cream containing paromomycin and gentamicin” NCT00703924 ↗ “Paromomycin + Gentamicin Topical Cream” NCT01988909 ↗ “Paromomycin” NCT02099240 ↗ |
| Known as | Aminosidin | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | aminosidine | “Pilot Randomized Study of Paromomycin (Aminosidine) vs Streptomycin for Uncomplicated Pulmonary Tuberculosis” NCT00004444 ↗ |
| Known as | Aminoxidin | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | ANTIBIOTIC 503-3 | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | ANTIBIOTIC SF 767B | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Catenulin | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Crestomycin | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Estomycin | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Farmiglucin | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Farminosidin | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Gabbromicina | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Gabbromycin | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Gabbroral | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Gabromycin | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Humagel | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Humatin | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Hydroxymycin | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Monomycin a | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Neomycin e | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | NSC-758421 | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Paramicina | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Paramomycin | “Doxycycline, Paramomycin, Clarithromycin, Clindamycin, Dapsone, Miltefosine” NCT02366884 ↗ |
| Known as | Pargonyl | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Paricina | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Paromomicina | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Paromomycin i | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Paromomycin Intramuscular Injection | “support registration of Paromomycin Intramuscular Injection (PMIM) as a low-cost treatment option in Bangladesh.” PMID 26496648 ↗ Oct 2015 |
| Known as | Paromomycin Sulfate | “Drug: Paromomycin Sulfate” NCT03096457 ↗ |
| Known as | Paromomycin sulphate | “Paromomycin sulphate (PM) has been shown to be efficacious for VL treatment in India.” PMID 22724029 ↗ Jun 2012 |
| Known as | Paromomycin-in-Aquaphilic | “Paromomycin-in-Aquaphilic had a cure rate of 77.5% (31 of 40 patients)” NCT03829917 ↗ |
| Known as | Paromomycine | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Paucimycin | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | PMIM | “support registration of Paromomycin Intramuscular Injection (PMIM) as a low-cost treatment option in Bangladesh.” PMID 26496648 ↗ Oct 2015 |
| Known as | Quintomycin c | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | R 400 | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Known as | Sinosid | ChEMBL registry synonym — accepted as the source's own label CHEMBL370143 ↗ |
| Modality | Small molecule | “paromomycin, an aminoglycoside” PMID 17582067 ↗ Jun 2007 |
| Route | Oral | “effectiveness of oral paromomycin sulfate” NCT00000771 ↗ |