Drugs / amsacrine
amsacrine
also known as
Acridinylanisidide · Amekrin · Amsacrina · AMSACRINE HYDROCHLORIDE · Amsidil · Amsidine · Amsidyl · CI-880 · +7 more
Trials 5
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 34 trials | ||||||
| Phase 3 | NCT00003436 | Jul 1998 → Dec 2005 | leukemia, myelodysplastic syndrome | Medical Research Council | Completed | No outcome recorded |
| Phase 3 | NCT00002719 | Dec 1995 → Nov 2001 | leukemia, neutropenia | European Organisation for Research and Treatment of Cancer - EORTC | Completed | No outcome recorded |
| Phase 3 | NCT00002658 | Jan 1994 → ? | leukemia, neutropenia | Medical Research Council | Unknown | No outcome recorded |
| Phase 3 | NCT01324063 | Nov 1986 → Jun 1994 | myeloid leukemia | European Organisation for Research and Treatment of Cancer - EORTC | Completed | No outcome recorded |
| Phase 41 trial · 1 missed | ||||||
| Phase 4 | NCT00180102 | Dec 2003 → Nov 2009 | acute myeloid leukemia | Technical University Dresden | Completed | Missed primary |
| Comparator or background therapy5 trials | ||||||
| Phase 1/2 | NCT05807932 Background | Jun 2023 → Apr 2029 expected | acute myeloid leukemia, chronic myelomonocytic leukemia, myelodysplastic syndrome | Heinrich-Heine University, Duesseldorf | Recruiting | No outcome recorded |
| Phase 1/2 | NCT00840684 Background | Jan 2009 → May 2011 | leukemia | Institut Paoli-Calmettes | Completed | No outcome recorded |
| Phase 2 | NCT01423175 Comparator | Jul 2011 → Jan 2015 | acute myeloid leukemia, myelodysplastic syndrome | Hannover Medical School | Unknown | No outcome recorded |
| Phase 2/3 | NCT01228331 Comparator | Oct 2010 → Dec 2019 | leukemia | University Medical Center Hamburg-Eppendorf | Completed | No outcome recorded |
| Phase 3 | NCT03765541 Background | Jan 2020 → May 2024 | acute myeloid leukemia | University Hospital, Toulouse | Terminated | No outcome recorded Stop: Enrollment |
Evidence & citations 18 cited values
Every value below carries the sentence it was read from. 11 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | amsacrine | “FLAMSA (consisting of one dose of fudarabine, amsacrine and ara-C for four days)” NCT01423175 ↗ |
| Known as | Acridinylanisidide | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | Amekrin | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | Amsacrina | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | AMSACRINE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | Amsidil | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | Amsidine | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | Amsidyl | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | CI-880 | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | Lamasine | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | M-AMSA | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | NCI-249992 | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | NSC-156303 | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | NSC-249992 | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | SN-11841 | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Known as | SN-21429 | ChEMBL registry synonym — accepted as the source's own label CHEMBL43 ↗ |
| Modality | Small molecule | — CHEMBL43 ↗ |
| Route | Intravenous | “amsacrine IV over 1 hour” NCT00002658 ↗ |