drugset / Trial / NCT00000259

Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11

NCT00000259

Non-randomizedCrossoverDouble-blind

Summary

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To examine sevoflurane versus isoflurane inhalation at subanesthetic concentrations on mood, pain, and psychomotor performance.

Timeline

Start
1996-08
Primary completion
1997-11
Completion
1997-11

Publications

  • Background Anesthesiology. 1997 (in press).

Drugs

EvaluationDrugModalityDoseRoute
Comparator Nitrous Oxide Other / unclassified 15 % Inhaled
Comparator Nitrous Oxide Other / unclassified 30 % Inhaled
Comparator Sevoflurane Other / unclassified 0.3 % Inhaled
Comparator Sevoflurane Other / unclassified 0.6 % Inhaled