drugset / Trial / NCT00002559

Combination Chemotherapy in Treating Patients With Germ Cell Tumors That Have Not Responded to Previous Cisplatin

NCT00002559

Phase 1/2 Completed 43 enrolled Memorial Sloan Kettering Cancer Center
Treatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of combination chemotherapy consisting of paclitaxel, cisplatin, and ifosfamide in treating patients who have ovarian or testicular germ cell tumors that are refractory to platinum-containing chemotherapy.

Timeline

Start
1994-01
Primary completion
2003-01
Completion
2003-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Paclitaxel Small molecule Intravenous
Background Cisplatin Other / unclassified Intravenous
Background Ifosfamide Small molecule Intravenous
Background filgrastim Protein / enzyme biologic Subcutaneous