drugset / Trial / NCT00002858

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Small Cell Lung Cancer

NCT00002858 ↗

Phase 3 Unknown 280 enrolled Gustave Roussy, Cancer Campus, Grand Paris
RandomizedTreatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one chemotherapy drug with radiation therapy may kill more tumor cells. It is not yet known which treatment regimen is more effective for small cell lung cancer. PURPOSE: Randomized phase III trial to study the effectiveness of combination chemotherapy using two different doses of cyclophosphamide followed by alternating chemotherapy and radiation therapy in treating patients with small cell lung cancer.

Timeline

Start
1993-03
Primary completion
—
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclophosphamide Other / unclassified — —
Background Cisplatin Other / unclassified — —
Background Doxorubicin Other / unclassified — —
Background Etoposide Small molecule — —