drugset / Trial / NCT00002989

Combination Chemotherapy With or Without Idarubicin and Peripheral Stem Cell Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome

NCT00002989

RandomizedTreatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of idarubicin plus peripheral stem cell transplantation using the patient's own or donated stem cells in treating patients with leukemia or myelodysplastic syndrome.

Timeline

Start
1997-03
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Busulfan Small molecule
Subject Cyclophosphamide Other / unclassified
Subject Idarubicin Small molecule
Subject Melphalan Small molecule Intravenous