Combination Chemotherapy in Treating Patients With Refractory or Recurrent Solid Tumors

Phase 1 Completed 73 enrolled Memorial Sloan Kettering Cancer Center National Cancer Institute (NCI) · collab

Treatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy with paclitaxel and cisplatin plus flavopiridol in treating patients who have refractory or recurrent solid tumors.

Timeline

Start: 1997-07
Primary completion: 2001-10
Completion: 2001-10

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cisplatin	Other / unclassified	—	Intravenous
Subject	Paclitaxel	Small molecule	—	Intravenous
Subject	alvocidib	Small molecule	—	Intravenous

Indications

No indication recorded.