drugset / Trial / NCT00003042
Chemotherapy and Stem Cell Transplantation in Treating Patients With Stage IIIB Breast Cancer
Non-randomizedParallel-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: This phase II trial is studying how well chemotherapy and stem cell transplantation work in treating patients with stage IIIB breast cancer.
Timeline
- Start
- 1997-05-30
- Primary completion
- 2010-02-09
- Completion
- 2025-11-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | — | — |
| Subject | Cyclophosphamide | Other / unclassified | — | Intravenous |
| Subject | Doxorubicin | Other / unclassified | — | Intravenous |
| Subject | Melphalan | Small molecule | — | — |
| Subject | Paclitaxel | Small molecule | — | Intravenous |
| Background | 2-MERCAPTOETHANESULFONIC ACID | Small molecule | — | — |
| Background | Tamoxifen | Small molecule | — | — |
| Background | filgrastim | Protein / enzyme biologic | — | Intravenous |