drugset / Trial / NCT00003166

Bryostatin and Vincristine in B-Cell Malignancies

NCT00003166

Phase 1 Completed 18 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase I trial is studying the side effects and best dose of bryostatin-1 when given together with vincristine in treating patients with chronic lymphocytic leukemia, non-Hodgkin's lymphoma, or multiple myeloma. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells

Timeline

Start
1998-05
Primary completion
2001-07
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject bryostatin 1 Small molecule Intravenous
Background Vincristine Small molecule Intravenous