drugset / Trial / NCT00003288
Tirapazamine Plus Cyclophosphamide in Treating Children With Refractory Solid Tumors
NaSingle-groupOpen-labelTreatment
Summary
Phase I trial to study the effectiveness of tirapazamine plus cyclophosphamide in treating children who have refractory solid tumors. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
Timeline
- Start
- 1998-08
- Primary completion
- 2003-06
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | — | Intravenous |
| Subject | tirapazamine | Small molecule | — | Intravenous |
| Background | filgrastim | Protein / enzyme biologic | — | Subcutaneous |