drugset / Trial / NCT00003388
Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma
Phase 2
Completed
38 enrolled
Eastern Cooperative Oncology Group
National Cancer Institute (NCI) · collab
Treatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy consisting of liposomal doxorubicin, cyclophosphamide, vincristine, and prednisone in treating patients with AIDS-related lymphoma.
Timeline
- Start
- 1999-07-26
- Primary completion
- 2003-04
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | — | Intravenous |
| Subject | Doxorubicin | Other / unclassified | — | Intravenous |
| Subject | Prednisone | Other / unclassified | — | Oral |
| Subject | Vincristine | Small molecule | — | Intravenous |
| Background | Cytarabine | Small molecule | — | Intrathecal |
| Background | Methotrexate | Small molecule | — | Intrathecal |
| Background | filgrastim | Protein / enzyme biologic | — | Subcutaneous |