drugset
drugset / Trial / NCT00003625

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma

NCT00003625 ↗

Phase 1 Completed 7 enrolled Children's Oncology Group National Cancer Institute (NCI) · collab
Open-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one chemotherapy drug with radiation therapy may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy plus radiation therapy in treating patients with newly diagnosed brain stem glioma.

Timeline

Start
1998-12
Primary completion
2001-02
Completion
2006-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Vincristine Small molecule 0.8 mg/m2 Intravenous
Background Cyclosporine Peptide — Intravenous
Background Etoposide Small molecule — Oral

Indications

brain neoplasm