drugset / Trial / NCT00003788

Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas

NCT00003788

Phase 3 Unknown 270 enrolled Colorado Health Foundation
RandomizedTreatment

Summary

RATIONALE: Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. It is not yet known if the addition of photodynamic therapy to combined therapy with surgery, radiation therapy, and chemotherapy is more effective than combined therapy alone for supratentorial gliomas. PURPOSE: Randomized phase III trial to study the effectiveness of surgery, radiation therapy, and chemotherapy with or without photodynamic therapy in treating patients who have newly diagnosed or recurrent malignant supratentorial gliomas.

Timeline

Start
1998-04
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject porfimer sodium Small molecule Intravenous
Background Lomustine Small molecule
Background carmustine Small molecule
Background procarbazine Small molecule