drugset / Trial / NCT00016016

Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Acute Leukemia

NCT00016016

Phase 1/2 Completed 53 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

Phase II trial to study the effectiveness of combining flavopiridol and cytarabine with mitoxantrone in treating patients who have acute leukemia. Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.

Timeline

Start
2001-02
Primary completion
2006-11
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject alvocidib Small molecule Intravenous
Background Cytarabine Small molecule Intravenous
Background Mitoxantrone Small molecule Intravenous