drugset / Trial / NCT00032188

Interleukin-2 and Bryostatin 1 in Treating Patients With Advanced Kidney Cancer

NCT00032188

Phase 2 Completed 65 enrolled National Cancer Institute (NCI)
RandomizedParallel-groupOpen-labelTreatment

Summary

Interleukin-2 may stimulate a person's white blood cells to kill tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining bryostatin 1 with interleukin-2 may cause a stronger immune response and kill more tumor cells. Randomized phase II trial to study the effectiveness of combining interleukin-2 and bryostatin 1 in treating patients who have advanced kidney cancer

Timeline

Start
2002-01
Primary completion
2006-06
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject bryostatin 1 Small molecule Intravenous
Background aldesleukin Protein / enzyme biologic Subcutaneous

Indications