drugset / Trial / NCT00054158

Combination Chemotherapy and Thalidomide in Treating Patients With Stage I, Stage II, or Stage III Multiple Myeloma

NCT00054158 ↗

Phase 2 Completed 24 enrolled Roswell Park Cancer Institute
Open-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. Combining chemotherapy with thalidomide may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy and thalidomide in treating patients who have newly diagnosed stage I, stage II, or stage III multiple myeloma.

Timeline

Start
2004-08
Primary completion
2006-04
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule — Oral
Subject Doxorubicin Other / unclassified — Intravenous
Subject Thalidomide Other / unclassified — Oral
Subject Vincristine Small molecule — Intravenous

Indications